Food safety
Foodborne illness: the germs, the numbers, the basic precautions
Key points
- WHO describes foodborne hazards as bacteria, viruses, parasites, prions and chemical substances.
- The global burden figures have a stated year and include multiple hazards.
- FDA names young children, older adults and people with weakened immunity among higher-risk groups.
- FDA’s general handling guidance covers cleaning, separation, cooking and chilling.

Foodborne illness is a broad subject involving infectious agents and other contaminants in food. The World Health Organization food-safety fact sheet groups hazards into bacteria, viruses, parasites, prions and chemical substances. Its account connects prevention with production, distribution and food handling, rather than with a single ingredient or farming method. This page presents general agency information and the FDA's basic handling guidance. this is general information, not medical advice.
What the global estimates measure
The WHO fact sheet reports more than 866 million cases of foodborne illness and 1.52 million deaths in 2021 in its global burden estimates. These are population estimates across multiple hazards, not the number of cases attributed to any one organism or food. The fact sheet describes the difficulty of estimation: many diseases are not under public-health surveillance, illness can go unreported, and establishing the connection between food contamination and an outcome can be difficult. The year and the scope are therefore part of the meaning of the figures.
A global estimate and an outbreak investigation serve different purposes. The first describes a broad burden across populations; the second examines a particular pattern of illnesses and possible sources. The FDA foodborne-pathogens page explains that its outbreak-response network works with state and local partners and other federal investigators to identify a cause and prevent additional illnesses. The agency also describes cooperation with producers over voluntary recalls and its mandatory recall authority under food law.
The organisms are varied
The FDA overview of foodborne illnesses describes organisms frequently involved in illness in the United States, including Salmonella, Campylobacter, particular E. coli strains, Listeria and noroviruses. Its table associates different organisms with different food sources and patterns of illness. Salmonella entries include eggs, poultry, meat and contaminated produce, while the E. coli entry includes undercooked beef, unpasteurized milk or juice and contaminated water. These are the agency's general associations, not a diagnosis or a conclusion about a particular meal.
WHO describes norovirus as a common cause of foodborne infection and explains that other viruses can also be transmitted through food. Its fact sheet separately discusses parasites and prions. This range matters because foodborne illness is not synonymous with bacterial contamination. The BSE and feed-rule page explains the prion subject separately; the disease process described there is different from the organisms commonly discussed in household handling guidance.
The FDA's foodborne-illness table also describes Listeria and its associations with unpasteurized dairy products and certain ready-to-eat meats. The FDA table describes different patterns of illness among different groups. WHO separately notes that Listeria can grow at refrigeration temperatures. These agency descriptions illustrate why an organism's name, a food source and the handling conditions all belong in an explanation. They do not provide a symptom checker or establish the cause of an individual's illness.
Some groups require particular attention in agency information
The FDA overview identifies very young people, older people and people with weakened immune systems as groups at greater risk of serious consequences from many foodborne illnesses. Its Listeria entry also discusses pregnancy. The agency's handling guidance names pregnant people, young children, older adults and people with weakened immunity as higher-risk groups. These categories are reported as the agency describes them; this reference does not assess anyone's individual condition, exposure or need for treatment.
FDA's basic handling guidance
The FDA food-handling page organizes its general advice around cleaning, separation, cooking and chilling. These headings describe different activities, from preparing a work surface to storing a perishable food. They are presented here as the agency's household guidance, not as claims that one step can settle every food-related question. The Food Safety Modernization Act page looks at the production and supply-chain rules that address a different part of prevention.
Clean and separate
Under cleaning, FDA advises washing hands and food-preparation surfaces, washing cutting boards and utensils after each food item, and rinsing fresh produce under running tap water. Under separation, it advises keeping raw meat, poultry, seafood and eggs apart from other foods during shopping and storage, and using separate cutting boards for produce and raw animal foods. It also advises washing a plate before using it for cooked food if it previously held raw animal food. These are handling practices attributed to FDA, rather than advice about which farming system to favor.
Cook and chill
The same FDA guidance explains that food color and texture are unreliable indicators and recommends a food thermometer for checking cooking temperatures. It also advises prompt refrigeration of perishables, thawing in a refrigerator, cold water or a microwave rather than on a counter, and dividing large amounts of leftovers into shallow containers for cooling. The agency provides food-specific temperatures in its own guide. This page summarizes the categories without inventing a new cooking schedule or extending the guidance to medical decisions.
Recalls and broader prevention
FDA’s recalls, market withdrawals and safety alerts page gathers information from certain public notices and explains that not every recall is posted there. Its purpose is to report identified product issues, rather than to rank diets or production systems. The irradiation page describes one regulated food-processing technology, while the antibiotic-resistance page covers another distinct question involving food animals and microorganisms. Keeping these subjects separate makes agency advice and policy decisions easier to interpret.