Land, water & climate

Pesticides and their residues on food

Key points

  • EPA distinguishes pesticide registration from tolerances for food residues.
  • A detected residue and a tolerance violation are different findings.
  • WHO describes an international assessment process used to develop maximum residue limits.
  • IARC, EPA and European bodies report assessments with differing scope and conclusions.
A honeybee on a clover blossom.

Pesticide questions involve several different subjects: approval for a specified use, residues remaining on food, environmental movement and the interpretation of health evidence. The EPA explanation of food and pesticides distinguishes registration from the legal limits called tolerances. A monitoring result, a hazard classification and a tolerance serve different purposes. This page reports the agencies' methods and positions, including disagreements, without assigning a general verdict to pesticides or advising readers what to buy or avoid.

Registration concerns specified uses

EPA's summary of the Federal Insecticide, Fungicide, and Rodenticide Act describes authority over pesticide distribution, sale, production and use. With specified exceptions, pesticides sold or distributed in the United States require registration. The agency explains that registration involves a statutory standard considering environmental costs and benefits and dietary risk under food law. A registered use therefore comes with conditions; the registration category is not an unrestricted description of every route, amount or circumstance of exposure.

Wikipedia's Food Quality Protection Act article records that the law was enacted in 1996, amended pesticide and food statutes, and established a health-based standard for pesticides used on food. It describes consideration of aggregate exposure to a pesticide from multiple sources and cumulative exposure to pesticides with common mechanisms. Those are different assessment questions. The law's framework asks the regulator to consider more than a single measurement on one food, while keeping attention on the particular substances and pathways under review.

A tolerance is a legal residue limit

The EPA food-and-pesticides page defines a tolerance as the maximum legal residue limit for a treated food and describes it as the level that triggers enforcement action when exceeded. It explains that the tolerance applies to domestic and imported food. In setting it, EPA considers the substance's properties, its application, breakdown products and residues when food reaches the market. This is the agency's account of a legal and assessment process, rather than this reference's assurance about any individual item.

Detection and enforcement are distinct questions in that account. EPA explains that laboratories can detect residues below the levels relevant to its standards, so a positive analytical result is not the same as a tolerance violation. The FDA pesticide-residue monitoring page provides annual reports and supporting data describing its monitoring program. The report, the analytical method and the relevant legal limit provide different kinds of information. A statement that a substance was detected is incomplete without the sampling context and the comparison being made.

International limits draw on a separate assessment process

The WHO pesticide-residue fact sheet describes the Joint FAO/WHO Meeting on Pesticide Residues, or JMPR, as an independent international group assessing evidence. Its account says the group draws on data submitted for national registrations and published research, then establishes acceptable daily intakes. Governments and bodies such as the Codex Alimentarius Commission use those assessments when setting maximum residue limits. These international reference limits should be distinguished from a particular national registration or enforcement decision.

Glyphosate: attributed conclusions and their scope

In its glyphosate account, the International Agency for Research on Cancer reports that it classified glyphosate as probably carcinogenic to humans in March 2015, based on limited evidence in humans and sufficient evidence in experimental animals. IARC explains that its monograph is a hazard classification, indicating the strength of evidence. It separately states that the probability of an outcome depends on exposure and the strength of the effect. The classification is reported here as IARC's conclusion, without converting it into a statement about a reader's dietary exposure.

The EPA glyphosate page reports that its 2017 assessment concluded glyphosate was not likely to be carcinogenic to humans and found no dietary risks of concern. The agency contrasts its examination of expected real-world exposure with IARC's hazard question concerning whether a chemical can cause cancer under any conditions. It describes a review including registration studies and other scientific material. The hazard-and-risk explainer examines those distinctions without treating the agencies' descriptions as interchangeable.

EFSA’s glyphosate topic page describes the European Chemicals Agency's hazard-assessment role and EFSA's exposure-based risk-assessment role. It lists a peer-review summary whose stated subjects are the absence of critical areas of concern and identified data gaps. The same page reports ECHA's conclusion that a carcinogenic classification was not justified on the available evidence. These attributed accounts distinguish European review responsibilities. The topic page identifies data gaps in the summary's title without setting out their detailed findings.

Drift is a question about movement beyond a target area

Wikipedia's dicamba article describes concern about movement from treated fields onto neighboring crops and reports EPA's identification of spray drift as its primary ecological risk for non-target terrestrial plants. The subject differs from measuring residues in a sampled food. The engineered-crop page connects herbicide-tolerant traits with these agricultural questions. The distinction between spray drift and food sampling is also a distinction between environmental and dietary assessment questions.

Research asks additional exposure questions

The National Institute of Environmental Health Sciences pesticide page describes research into pesticide exposures and health, including the Agricultural Health Study of farmers and their spouses. It distinguishes types of pesticides and routes such as ingestion, breathing and skin contact. Research populations and exposure patterns matter when interpreting findings, so a worker-exposure study cannot simply be relabeled a food-residue conclusion. The rulemaking page explains how evidence enters regulatory procedures, and the organic-standard page describes a production and labeling framework rather than a verdict on all residues.